This document addresses requirements, technologies, and interoperability and standards for e-infrastructure to support existing, ongoing, and future research in the European Research Area. The term e-infrastructure encompasses the distributed information and communications technologies (ICTs), together with federating software, that together provide services and access to resources needed to support public sectors such as research in the natural and social sciences and humanities. While not a focus of this specific document, some consideration is given to aspects of e-infrastructure that apply also to e-government.

 The document includes use cases and position papers collected for the Cloudscape III  event, serving primarily as a sample of the cloud computing landscape. They highlight potential challenges for deliberation at Cloudscape III and for the SIENA Roadmap Editorial Board in the coming months, with the aim of shaping future developments and the SIENA Roadmap itself.